منابع مشابه
Effect of dexamethasone on carrageenin-induced inflammation in the lung
To study the anti-inflammatory mechanisms of glucocorticoids, we have compared the effects of intratracheal carrageenin (2.5 mg) on control rats and those in which inflammation was subdued by prior dexamethasone treatment (10 mg/l in drinking water). Inflammation was maximal 48 h post-carrageenin. After dexamethasone, carrageenin caused tittle inflammation or oedema (wet lung (mg), n = 6, mean ...
متن کاملThe enzymic hydrolysis of carrageenin.
Carrageenin is the water soluble polysaccharide extractable from the red algae Chondrus crispus and Gigartina stellata. The polysaccharide is essentially a polymer of alpha-D-galactopyranoside-4-sulphate. Smith et al. (1954) fractionated carrageenin with potassium chloride into two components and obtained a precipitable component which could form gels and a nongelling component which remained i...
متن کاملInhibitory effects of proanthocyanidins from Ribes nigrum leaves on carrageenin acute inflammatory reactions induced in rats
BACKGROUND The anti-inflammatory effects of proanthocyanidins (PACs), isolated from blackcurrant (Ribes nigrum L.) leaves, were analysed using carrageenin-induced paw oedema and carrageenin-induced pleurisy in rats. RESULTS Pretreatment of the animals with PACs (10, 30, 60 and 100 mg/kg, i.p.) reduced paw oedema induced by carrageenin in a dose and time-dependent manner. PACs also inhibited d...
متن کاملAmeliorative Effect of Young Leaves of Triticum Aestivum on Carrageenin Induced Inflammation
Young leaves of Triticum aestivum is commonly known as Wheatgrass and has been widely used in the traditional system for the treatment of a variety of diseases. In this study we have used ninth day wheat grass methanolic extract of the shade dried drug for its anti-inflammatory & analgesic activities. . It was carried out using Carrageenan induced paw edema volume, Hot plate and Writhing respon...
متن کاملInvolvement of Nitric Oxide in a Rat Model of Carrageenin-Induced Pleurisy
Some evidence indicates that nitric oxide (NO) contributes to inflammation, while other evidence supports the opposite conclusion. To clarify the role of NO in inflammation, we studied carrageenin-induced pleurisy in rats treated with an NO donor (NOC-18), a substrate for NO formation (L-arginine), and/or an NO synthase inhibitor (S-(2-aminoethyl) isothiourea or N(G)-nitro-L-arginine). We asses...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 1977
ISSN: 0004-3591,1529-0131
DOI: 10.1002/art.1780200313